Photobiomodulation and antimicrobial photodynamic therapy as adjunct in the treatment and prevention of osteoradionecrosis of the jaws: A case report.

CASE REPORT: We report on a patient with a history of radiotherapy to the head and neck region exhibiting necrotic bone exposure associated with fistula and purulent exudation in the mandible, with the diagnosis of stage 3 osteoradionecrosis, in addition to a periapical cyst in the maxillary anterior region and multiple root remnants. An antibiotic coverage protocol with amoxicillin and metronidazole was prescribed for subsequent necrotic bone removal. The surgical procedure was performed along with the aPDT using methylene blue and red light, followed by coaptation of the edges of the surgical wound and the healing protocol with LLLT. The extraction of non-rehabilitated teeth was performed two per session using antibiotic coverage, aPDT, and LLLT and mouthwash with 0.12 % chlorhexidine was prescribed until the complete closure of the surgical wound was achieved. Additionally, two aPDT sessions and four LLLT protocols were performed for complete healing of the surgical sites. Extra and intraoral examinations and panoramic and periapical radiographs were performed. No emergence or recurrence of osteonecrosis was observed after 12 months of follow-up.

Multiple brown tumours of tertiary hyperparathyroidism in a renaltransplant recipient: A case report

Tertiary Hyperparathyroidism (HPT) is an uncommon condition that affects patients with secondary HPT aftera successful kidney transplant. Bone alterations are the main consequences of this endocrine condition, includingthe development of an osteolytic lesion called brown tumour. This paper reports an unusual case of multiplebrown tumours located in the maxilla and mandible in a 58-year-old renal transplant recipient, with tertiary HPT.Incisional biopsies were performed and, in both samples, the histopathological diagnoses were giant cell lesions.Due to these diagnoses, the medical history of chronic renal failure, and high levels of serum calcium and PTH,lesions were diagnosed as multiple brown tumours of tertiary HPT. The lesions showed regression within the twomonths following a total parathyroidectomy. Minimal local interventions were established to make an early diagnosisand to treat these lesions. The diagnosis of primary oral lesions was very important in order to demonstratethe relevance of interdisciplinary activity and the inclusion of dentists as part of organ transplant units (AU)

No disponible

Multiple brown tumours of tertiary hyperparathyroidism in a renal transplant recipient: a case report.

Tertiary Hyperparathyroidism (HPT) is an uncommon condition that affects patients with secondary HPT after a successful kidney transplant. Bone alterations are the main consequences of this endocrine condition, including the development of an osteolytic lesion called brown tumour. This paper reports an unusual case of multiple brown tumours located in the maxilla and mandible in a 58-year-old renal transplant recipient, with tertiary HPT. Incisional biopsies were performed and, in both samples, the histopathological diagnoses were giant cell lesions. Due to these diagnoses, the medical history of chronic renal failure, and high levels of serum calcium and PTH, lesions were diagnosed as multiple brown tumours of tertiary HPT. The lesions showed regression within the two months following a total parathyroidectomy. Minimal local interventions were established to make an early diagnosis and to treat these lesions. The diagnosis of primary oral lesions was very important in order to demonstrate the relevance of interdisciplinary activity and the inclusion of dentists as part of organ transplant units.